FTS (First Trimester Screening)

An optional, non-invasive blood screening test and ultrasound evaluation of the fetus to identify risks for specific chromosome abnormalities such as Down Syndrome.

An optional, non-invasive blood screening test and ultrasound evaluation of the fetus to identify risks for specific chromosome abnormalities such as Down Syndrome.
An image by LMFM in relation to - This is Important
An image by LMFM in relation to - This is Important

This is Important

What is a First Trimester Screening?


First trimester screening (FTS) is a safe, non-invasive way to assess your baby’s risk for certain chromosomal conditions—most commonly Down syndrome (trisomy 21), trisomy 18, and trisomy 13—early in pregnancy. Performed between 11 and 13 weeks, FTS combines a simple blood draw with a specialized ultrasound measurement called nuchal translucency (NT). The blood test analyzes pregnancy-associated plasma protein A (PAPP-A) and free β-hCG hormone levels, while the NT ultrasound measures the fluid at the back of your baby’s neck. By integrating these two data points, our maternal–fetal medicine team provides you with a personalized risk estimate. Remember, FTS is a screening tool, not a diagnosis—an “increased risk” result simply means that additional testing may be warranted.

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How Do First Trimester Screenings Work?


When you arrive for your FTS appointment, we’ll begin with a quick blood sample drawn by one of our experienced phlebotomists. Next, a certified sonographer will perform the nuchal translucency ultrasound, carefully measuring the fluid collection behind your baby’s neck. Both tests take just minutes, and you can typically return to your normal routine immediately afterward. Our specialists then combine your blood markers, ultrasound findings, and your personal medical information—such as age and health history—to calculate a comprehensive risk score. Most results are available within one week, and our team will review them with you in detail to ensure you fully understand your options.

Benefits of Early Screening

Opting for FTS offers valuable peace of mind by identifying pregnancies with an elevated chance of chromosomal abnormalities at a time when follow-up diagnostics are still minimally invasive. Early detection gives you and your care team the greatest flexibility: if further testing like chorionic villus sampling (CVS) or amniocentesis is recommended, it can be scheduled sooner, when risks and recovery times are lower. Knowing early also allows you to access specialized counseling and support services tailored to your results. Even if your screening indicates a low risk, you’ll gain reassurance and can proceed with confidence through your pregnancy. At Lancaster MFM, we believe that informed parents make empowered decisions, and FTS is a cornerstone of that process.

Is First Trimester Screening Right for You?

FTS is available to all pregnant individuals who want early insight into their baby’s chromosomal health, regardless of age or risk factors. It is especially recommended if you have a personal or family history of genetic conditions, or if you prefer to gather as much information as possible during the first trimester. Because this screening is non-diagnostic and poses no risk to your developing baby, many parents choose it simply for the reassurance it provides. If your results indicate an elevated risk, our maternal–fetal medicine specialists will walk you through the next steps—whether that means advanced diagnostic testing or referrals to genetic counseling. You remain in control every step of the way.



Ready for the Next Step?

Request an appointment today and discover why families trust Lancaster MFM for exceptional care, from preconception counseling through a healthy delivery. We’re here to support you—every heartbeat of the way.

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I had a beautiful experience with MFM. It was my first baby and they did a beautiful job taking care of us both. They understood that as a black women being in any medical space can be uncomfortable or scary especially when it comes to labor and birth. They always were so welcoming when I came into the office, the whole staff knew me by name they were also amazing with communication with not only myself but also my doctors at my obgyn. My baby was on the small side and everyone was diligent on keeping an eye on her . Let just say MFM does not play about their patients, because of them and their care both my baby and I had a safe and peaceful delivery at the end of pregnancy . I will absolutely be going back to them whenever I have another child. Thank you so much for your support and care. Baby girl and I absolutely love you guys.

Jp Gp

The staff were all so welcoming from the very first visit. The care received was very thorough and I trusted that my baby and I were in safe hands. Other providers can make it seem like they know it all and know what’s best for you/baby and don’t always listen. I did not get that feeling here. I felt very comfortable and it feels like family. Thank you LMFM!

A.S

The whole staff is very nice, caring and attentive. I feel safe and secure in my high risk pregnancy. I feel heard. They are all so loving. I wish I had came sooner with my first pregnancy but so happy I got to see them my second pregnancy. Also love being able to see my baby every visit.

Tiarra Champion

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